The effectiveness of mupirocin for acne is largely dependent upon the individual, the cause of the acne, and the specifics of the prescription. This variation results in a disparity of results, meaning the success for one person does not necessarily translate into success for a different individual. For this reason, it is difficult to generalize the effectiveness of mupirocin.
Acne is a common skin disease characterized by a number of aesthetically compromising physical effects, including scaly skin, redness, and the presence of infected pustules. The cause of acne involves genetic susceptibility, hormonal changes, and personal hygiene, which may contribute to the existence of acne-causing bacteria. Some people are born with acne-prone skin, whereas others may seldom experience a breakout. Hormonal changes brought on by the onset of puberty contribute to acne forming, and because bacteria is the culprit for this skin disease, poor hygiene may also be at fault in some sufferers.
Mupirocin is a commonly used antibiotic for the treatment of many bacteria-driven issues. This antibiotic is marketed most commonly as Bactroban® and is typically applied topically for the treatment of infections. It is composed as a medley of pseudonomic acids, effectively targeting bacteria through a mechanism that utilizes the prevention of RNA synthesis. RNA is a critical component of transferring genetic material, and its inhibition prevents bacterial replication, in turn eliminating the potential for spreading the infection.
Although using mupirocin for acne and other conditions is sometimes very useful, its use is also accompanied with potentially adverse effects. Skin irritation and allergic reactions are both possible, but the most dangerous reaction typical of mupirocin use is bacteria resistance. Similar to the process of natural selection, bacteria treated with antibiotics over time can evolve in a manner that leaves resistant species. These resistant species may not be affected by antibiotics, leaving them able to spread beyond control.
A great deal of variation exists for the effectiveness of mupirocin for treating acne among those who have used it. The majority experience success, as this antibiotic is very good at killing acne-causing bacteria. This success is most often short-lived, however, due to the immediate onset of resistant strains. Additionally, the expenses related to mupirocin make it difficult to afford for more chronic use. The potential risks and benefits should be assessed by each person with the help of a healthcare professional.